A monoclonal antibody raised against bacterially expressed MPV17 sequences shows peroxisomal, endosomal and lysosomal localisation in U2OS cells

Recessive mutations in the MPV17 gene cause mitochondrial DNA depletion syndrome, a fatal infantile genetic liver disease in humans. Loss of function in mice leads to glomerulosclerosis and sensineural deafness accompanied with mitochondrial DNA depletion. Mutations in the yeast homolog Sym1, and in...

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Detalles Bibliográficos
Autores principales: Weiher, Hans, Pircher, Haymo, Jansen-Dürr, Pidder, Hegenbarth, Silke, Knolle, Percy, Grunau, Silke, Vapola, Miia, Hiltunen, J. Kalervo, Zwacka, Ralf M., Schmelzer, Elmon, Reumann, Kerstin, Will, Hans
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4769525/
https://www.ncbi.nlm.nih.gov/pubmed/26921094
http://dx.doi.org/10.1186/s13104-016-1939-0

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