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Influenza H3N2 infection of the collaborative cross founder strains reveals highly divergent host responses and identifies a unique phenotype in CAST/EiJ mice
BACKGROUND: Influenza A virus is a zoonotic pathogen that poses a major threat to human and animal health. The severe course of influenza infection is not only influenced by viral virulence factors but also by individual differences in the host response. To determine the extent to which the genetic...
Autores principales: | Leist, Sarah R., Pilzner, Carolin, van den Brand, Judith M.A., Dengler, Leonie, Geffers, Robert, Kuiken, Thijs, Balling, Rudi, Kollmus, Heike, Schughart, Klaus |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4769537/ https://www.ncbi.nlm.nih.gov/pubmed/26921172 http://dx.doi.org/10.1186/s12864-016-2483-y |
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