Cargando…

Radix Puerariae lobatae (Gegen) suppresses the anticoagulation effect of warfarin: a pharmacokinetic and pharmacodynamics study

BACKGROUND: Radix Salvia miltiorrhiza (Danshen) and Radix Puerariae lobatae (Gegen) are used in Traditional Chinese Medicine to treat cardiovascular diseases. However, adverse herb-drug interactions were observed between warfarin and herbal remedies containing Danshen and Gegen. This study aims to i...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ge, Beikang, Zhang, Zhen, Zuo, Zhong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4769563/ https://www.ncbi.nlm.nih.gov/pubmed/26925159 http://dx.doi.org/10.1186/s13020-016-0078-9

Ejemplares similares

Relevance of the Pharmacokinetic and Pharmacodynamic Profiles of Puerariae lobatae Radix to Aggregation of Multi-Component Molecules in Aqueous Decoctions
por: Su, Bili, et al.
Publicado: (2016)

Use of Network Pharmacology to Explore the Mechanism of Gegen (Puerariae lobatae Radix) in the Treatment of Type 2 Diabetes Mellitus Associated with Hyperlipidemia
por: Yuan, Guozhen, et al.
Publicado: (2021)

Associated-Extraction Efficiency of Six Cyclodextrins on Various Flavonoids in Puerariae Lobatae Radix
por: Feng, Tao, et al.
Publicado: (2018)

Development on porous particles of Pueraria lobatae Radix for improving its compactibility and dissolution
por: Zhou, MiaoMiao, et al.
Publicado: (2018)

Safety of high‐dose Puerariae Lobatae Radix in adolescent rats based on metabolomics
por: Chen, Limei, et al.
Publicado: (2020)

Novel Carbon Dots Derived from Puerariae lobatae Radix and Their Anti-Gout Effects
por: Wang, Xiaoke, et al.
Publicado: (2019)

Combined Network Pharmacology and Molecular Docking to Verify the Treatment of Type 2 Diabetes with Pueraria Lobata Radix and Salviae Miltiorrhizae Radix
por: Mao, Jingxin, et al.
Publicado: (2023)

Rapid Determination of Puerarin by Near-infrared Spectroscopy During Percolation and Concentration Process of Puerariae Lobatae Radix
por: Jintao, Xue, et al.
Publicado: (2016)

Puerariae lobatae Radix Alleviates Pre-Eclampsia by Remodeling Gut Microbiota and Protecting the Gut and Placental Barriers
por: Huang, Liping, et al.
Publicado: (2022)

Updates on the Clinical Evidenced Herb-Warfarin Interactions
por: Ge, Beikang, et al.
Publicado: (2014)

Simultaneous Determination of Six Isoflavones from Puerariae Lobatae Radix by CPE-HPLC and Effect of Puerarin on Tyrosinase Activity
por: Qu, Limin, et al.
Publicado: (2020)

An Alternative Pathway for Formononetin Biosynthesis in Pueraria lobata
por: Li, Jia, et al.
Publicado: (2016)

Brain Pharmacokinetics and the Pharmacological Effects on Striatal Neurotransmitter Levels of Pueraria lobata Isoflavonoids in Rat
por: Xiao, Bingxin, et al.
Publicado: (2017)

Potential Anti-Diabetic Activity of Pueraria lobata Flower (Flos Puerariae) Extracts
por: Lertpatipanpong, Pattawika, et al.
Publicado: (2020)

Efficacy and Mechanism of Pueraria lobata and Pueraria thomsonii Polysaccharides in the Treatment of Type 2 Diabetes
por: Wang, Zhujun, et al.
Publicado: (2022)

Comparative analysis of the medicinal and nutritional components of different varieties of Pueraria thomsonii and Pueraria lobata
por: Fu, Mei, et al.
Publicado: (2023)

Puerariae lobatae radix protects against UVB-induced skin aging via antagonism of REV-ERBα in mice
por: Ma, Luyao, et al.
Publicado: (2022)

Chemical Constituents of the Flowers of Pueraria lobata and Their Cytotoxic Properties
por: Kim, Yejin, et al.
Publicado: (2022)

The effect of soil environmental factors on the yield and quality of Pueraria lobata
por: Li, Fahuo, et al.
Publicado: (2023)

Daidzein is the in vivo active compound of Puerariae Lobatae Radix water extract for muscarinic receptor-3 inhibition against overactive bladder
por: Qiang, Yining, et al.
Publicado: (2022)

Transcriptomic landscape of Pueraria lobata demonstrates potential for phytochemical study
por: Han, Rongchun, et al.
Publicado: (2015)

Identification of Three (Iso)flavonoid Glucosyltransferases From Pueraria lobata
por: Wang, Xin, et al.
Publicado: (2019)

Absolute Quantification of Isoflavones in the Flowers of Pueraria lobata by qHNMR
por: Thapa, Punam, et al.
Publicado: (2022)

Extraction of isoflavones from Puerariae lobata using subcritical water
por: Zhang, Hongguang, et al.
Publicado: (2018)

An Acidic Heteropolysaccharide Isolated from Pueraria lobata and Its Bioactivities
por: Zhao, Shifan, et al.
Publicado: (2023)

Pueraria lobata polysaccharides alleviate neonatal calf diarrhea by modulating gut microbiota and metabolites
por: Shen, Liuhong, et al.
Publicado: (2023)

Intestinal absorbability of three Radix Puerariae isoflavones including daidzein, daidzin and puerarin
por: Zhang, Li, et al.
Publicado: (2011)

Enzyme-Site Blocking Combined with Optimization of Molecular Docking for Efficient Discovery of Potential Tyrosinase Specific Inhibitors from Puerariae lobatae Radix
por: Liu, Haichun, et al.
Publicado: (2018)

Safety evaluation of root extract of Pueraria lobata and Scutellaria baicalensis in rats
por: Song, Jungbin, et al.
Publicado: (2020)

The complete chloroplast genome sequence of the Pueraria lobata (Willd.) Ohwi (Leguminosae)
por: Cao, Tianxu, et al.
Publicado: (2020)

Studies on Chemical Composition of Pueraria lobata and Its Anti-Tumor Mechanism
por: Fang, Xiaoxue, et al.
Publicado: (2022)

Comparative Transcriptome Analysis Provides Insights into the Resistance in Pueraria [Pueraria lobata (Willd.) Ohwi] in Response to Pseudo-Rust Disease
por: Huang, Xinlu, et al.
Publicado: (2022)

Edible Pueraria lobata-Derived Exosomes Promote M2 Macrophage Polarization
por: Wu, Jiaqi, et al.
Publicado: (2022)

Rapid Determination of 30 Polyphenols in Tongmai Formula, a Combination of Puerariae Lobatae Radix, Salviae Miltiorrhizae Radix et Rhizoma, and Chuanxiong Rhizoma, via Liquid Chromatography-Tandem Mass Spectrometry
por: Wang, Fu-Rong, et al.
Publicado: (2017)

Anti-Inflammatory Effects of Total Isoflavones from Pueraria lobata on Cerebral Ischemia in Rats
por: Lim, Dong Wook, et al.
Publicado: (2013)

A Novel and Effective Chromatographic Approach to the Separation of Isoflavone Derivatives from Pueraria lobata
por: Fu, Jiang, et al.
Publicado: (2015)

Support Vector Regression Approach to Predict the Design Space for the Extraction Process of Pueraria lobata
por: Wang, Yaqi, et al.
Publicado: (2018)

Thermal Inactivation Kinetics of Kudzu (Pueraria lobata) Polyphenol Oxidase and the Influence of Food Constituents
por: Liu, Junping, et al.
Publicado: (2021)

Mixed infection of an emaravirus, a crinivirus, and a begomovirus in Pueraria lobata (Willd) Ohwi
por: Liang, Xiaofei, et al.
Publicado: (2022)

Evaluation of pathways to the C‐glycosyl isoflavone puerarin in roots of kudzu ( Pueraria montana lobata)
por: Adolfo, Laci M., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_84bfje8d4q9q93anfl7cnj4pum