Molecular characterization of eluxadoline as a potential ligand targeting mu-delta opioid receptor heteromers

Eluxadoline, an orally active mixed μ opioid receptor (μOR) agonist δ opioid receptor (δOR) antagonist developed for the treatment of diarrhea-predominant irritable bowel syndrome, normalizes gastrointestinal (GI) transit and defecation under conditions of novel environment stress or post-inflammato...

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Detalles Bibliográficos
Autores principales: Fujita, Wakako, Gomes, Ivone, Dove, Leonard S., Prohaska, David, McIntyre, Gail, Devi, Lakshmi A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4769596/
https://www.ncbi.nlm.nih.gov/pubmed/25261794
http://dx.doi.org/10.1016/j.bcp.2014.09.015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4769596/
https://www.ncbi.nlm.nih.gov/pubmed/25261794
http://dx.doi.org/10.1016/j.bcp.2014.09.015

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