Sulfatide Preserves Insulin Crystals Not by Being Integrated in the Lattice but by Stabilizing Their Surface

Background. Sulfatide is known to chaperone insulin crystallization within the pancreatic beta cell, but it is not known if this results from sulfatide being integrated inside the crystal structure or by binding the surface of the crystal. With this study, we aimed to characterize the molecular mech...

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Detalles Bibliográficos
Autores principales: Buschard, Karsten, Bracey, Austin W., McElroy, Daniel L., Magis, Andrew T., Osterbye, Thomas, Atkinson, Mark A., Bailey, Kate M., Posgai, Amanda L., Ostrov, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4769769/
https://www.ncbi.nlm.nih.gov/pubmed/26981544
http://dx.doi.org/10.1155/2016/6179635

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