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Automated Spatial Brain Normalization and Hindbrain White Matter Reference Tissue Give Improved [(18)F]-Florbetaben PET Quantitation in Alzheimer's Model Mice
Preclinical PET studies of β-amyloid (Aβ) accumulation are of growing importance, but comparisons between research sites require standardized and optimized methods for quantitation. Therefore, we aimed to evaluate systematically the (1) impact of an automated algorithm for spatial brain normalizatio...
Autores principales: | Overhoff, Felix, Brendel, Matthias, Jaworska, Anna, Korzhova, Viktoria, Delker, Andreas, Probst, Federico, Focke, Carola, Gildehaus, Franz-Josef, Carlsen, Janette, Baumann, Karlheinz, Haass, Christian, Bartenstein, Peter, Herms, Jochen, Rominger, Axel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4770021/ https://www.ncbi.nlm.nih.gov/pubmed/26973442 http://dx.doi.org/10.3389/fnins.2016.00045 |
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