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Prospective Evaluation of Sleep Apnea as Manifestation of Heart Failure in Children
In adults with heart failure, central sleep apnea (CSA), often manifested as Cheyne–Stokes respiration, is common, and has been associated with adverse outcome. Heart failure in children is commonly caused by dilated cardiomyopathy (DCM). It is unknown whether children with heart failure secondary t...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4770058/ https://www.ncbi.nlm.nih.gov/pubmed/26474863 http://dx.doi.org/10.1007/s00246-015-1269-3 |
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author | den Boer, Susanna L. Joosten, Koen F. M. van den Berg, Sandra Backx, Ad P. C. M. Tanke, Ronald B. du Marchie Sarvaas, Gideon J. Helbing, Willem A. Rammeloo, Lukas A. J. ten Harkel, Arend D. J. van Iperen, Gabriëlle G. Dalinghaus, Michiel |
author_facet | den Boer, Susanna L. Joosten, Koen F. M. van den Berg, Sandra Backx, Ad P. C. M. Tanke, Ronald B. du Marchie Sarvaas, Gideon J. Helbing, Willem A. Rammeloo, Lukas A. J. ten Harkel, Arend D. J. van Iperen, Gabriëlle G. Dalinghaus, Michiel |
author_sort | den Boer, Susanna L. |
collection | PubMed |
description | In adults with heart failure, central sleep apnea (CSA), often manifested as Cheyne–Stokes respiration, is common, and has been associated with adverse outcome. Heart failure in children is commonly caused by dilated cardiomyopathy (DCM). It is unknown whether children with heart failure secondary to DCM have CSA, and whether CSA is related to the severity of heart failure. In this prospective observational study, 37 patients (<18 year) with heart failure secondary to DCM were included. They underwent polysomnography, clinical and laboratory evaluation and echocardiographic assessment. After a median follow-up time of 2 years, eight patients underwent heart transplantation. CSA (apnea–hypopnea index [AHI] ≥1) was found in 19 % of the patients. AHI ranged from 1.2 to 4.5/h. The occurrence of CSA was not related to the severity of heart failure. Three older patients showed a breathing pattern mimicking Cheyne–Stokes respiration, two of whom required heart transplantation. CSA was found in 19 % of the children with heart failure secondary to DCM. No relation was found with the severity of heart failure. In a small subset of children with severe DCM, a pattern mimicking Cheyne–Stokes respiration was registered. |
format | Online Article Text |
id | pubmed-4770058 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Springer US |
record_format | MEDLINE/PubMed |
spelling | pubmed-47700582016-04-09 Prospective Evaluation of Sleep Apnea as Manifestation of Heart Failure in Children den Boer, Susanna L. Joosten, Koen F. M. van den Berg, Sandra Backx, Ad P. C. M. Tanke, Ronald B. du Marchie Sarvaas, Gideon J. Helbing, Willem A. Rammeloo, Lukas A. J. ten Harkel, Arend D. J. van Iperen, Gabriëlle G. Dalinghaus, Michiel Pediatr Cardiol Original Article In adults with heart failure, central sleep apnea (CSA), often manifested as Cheyne–Stokes respiration, is common, and has been associated with adverse outcome. Heart failure in children is commonly caused by dilated cardiomyopathy (DCM). It is unknown whether children with heart failure secondary to DCM have CSA, and whether CSA is related to the severity of heart failure. In this prospective observational study, 37 patients (<18 year) with heart failure secondary to DCM were included. They underwent polysomnography, clinical and laboratory evaluation and echocardiographic assessment. After a median follow-up time of 2 years, eight patients underwent heart transplantation. CSA (apnea–hypopnea index [AHI] ≥1) was found in 19 % of the patients. AHI ranged from 1.2 to 4.5/h. The occurrence of CSA was not related to the severity of heart failure. Three older patients showed a breathing pattern mimicking Cheyne–Stokes respiration, two of whom required heart transplantation. CSA was found in 19 % of the children with heart failure secondary to DCM. No relation was found with the severity of heart failure. In a small subset of children with severe DCM, a pattern mimicking Cheyne–Stokes respiration was registered. Springer US 2015-10-16 2016 /pmc/articles/PMC4770058/ /pubmed/26474863 http://dx.doi.org/10.1007/s00246-015-1269-3 Text en © The Author(s) 2015 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. |
spellingShingle | Original Article den Boer, Susanna L. Joosten, Koen F. M. van den Berg, Sandra Backx, Ad P. C. M. Tanke, Ronald B. du Marchie Sarvaas, Gideon J. Helbing, Willem A. Rammeloo, Lukas A. J. ten Harkel, Arend D. J. van Iperen, Gabriëlle G. Dalinghaus, Michiel Prospective Evaluation of Sleep Apnea as Manifestation of Heart Failure in Children |
title | Prospective Evaluation of Sleep Apnea as Manifestation of Heart Failure in Children |
title_full | Prospective Evaluation of Sleep Apnea as Manifestation of Heart Failure in Children |
title_fullStr | Prospective Evaluation of Sleep Apnea as Manifestation of Heart Failure in Children |
title_full_unstemmed | Prospective Evaluation of Sleep Apnea as Manifestation of Heart Failure in Children |
title_short | Prospective Evaluation of Sleep Apnea as Manifestation of Heart Failure in Children |
title_sort | prospective evaluation of sleep apnea as manifestation of heart failure in children |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4770058/ https://www.ncbi.nlm.nih.gov/pubmed/26474863 http://dx.doi.org/10.1007/s00246-015-1269-3 |
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