Arsenic trioxide inhibits viability and induces apoptosis through reactivating the Wnt inhibitor secreted frizzled related protein-1 in prostate cancer cells

BACKGROUND: Growing evidence suggests that arsenic trioxide (As(2)O(3)) induces apoptosis and inhibits tumor cell growth in prostate cancer (PCa), although details of the mechanism are still inconclusive. We investigated the antitumor effect of As(2)O(3) in human PCa cell lines LNCaP and PC3 and the...

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Detalles Bibliográficos
Autores principales: Zheng, Lei, Jiang, Hui, Zhang, Zhi-Wei, Wang, Ke-Nan, Wang, Qi-Fei, Li, Quan-Lin, Jiang, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4770067/
https://www.ncbi.nlm.nih.gov/pubmed/26966376
http://dx.doi.org/10.2147/OTT.S92129

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4770067/
https://www.ncbi.nlm.nih.gov/pubmed/26966376
http://dx.doi.org/10.2147/OTT.S92129

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