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Subnanometre enzyme mechanics probed by single-molecule force spectroscopy

Enzymes are molecular machines that bind substrates specifically, provide an adequate chemical environment for catalysis and exchange products rapidly, to ensure fast turnover rates. Direct information about the energetics that drive conformational changes is difficult to obtain. We used subnanometr...

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Detalles Bibliográficos
Autores principales: Pelz, Benjamin, Žoldák, Gabriel, Zeller, Fabian, Zacharias, Martin, Rief, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4770092/
https://www.ncbi.nlm.nih.gov/pubmed/26906294
http://dx.doi.org/10.1038/ncomms10848

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