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Blockade of Kv1.5 channels by the antidepressant drug sertraline

Sertraline, a selective serotonin reuptake inhibitor (SSRI), has been reported to lead to cardiac toxicity even at therapeutic doses including sudden cardiac death and ventricular arrhythmia. And in a SSRI-independent manner, sertraline has been known to inhibit various voltage-dependent channels, w...

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Detalles Bibliográficos
Autores principales: Lee, Hyang Mi, Hahn, Sang June, Choi, Bok Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Physiological Society and The Korean Society of Pharmacology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4770110/
https://www.ncbi.nlm.nih.gov/pubmed/26937216
http://dx.doi.org/10.4196/kjpp.2016.20.2.193