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Blockade of Kv1.5 channels by the antidepressant drug sertraline
Sertraline, a selective serotonin reuptake inhibitor (SSRI), has been reported to lead to cardiac toxicity even at therapeutic doses including sudden cardiac death and ventricular arrhythmia. And in a SSRI-independent manner, sertraline has been known to inhibit various voltage-dependent channels, w...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Korean Physiological Society and The Korean Society of Pharmacology
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4770110/ https://www.ncbi.nlm.nih.gov/pubmed/26937216 http://dx.doi.org/10.4196/kjpp.2016.20.2.193 |