Cargando…

Effects of prunetin on the proteolytic activity, secretion and gene expression of MMP-3 in vitro and production of MMP-3 in vivo

We investigated whether prunetin affects the proteolytic activity, secretion, and gene expression of matrix metalloproteinase-3 (MMP-3) in primary cultured rabbit articular chondrocytes, as well as in vivo production of MMP-3 in the rat knee joint to evaluate the potential chondroprotective eff ect...

Descripción completa

Detalles Bibliográficos
Autores principales:	Nam, Dae Cheol, Kim, Bo Kun, Lee, Hyun Jae, Shin, Hyun-Dae, Lee, Choong Jae, Hwang, Sun-Chul
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Korean Physiological Society and The Korean Society of Pharmacology 2016
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4770113/ https://www.ncbi.nlm.nih.gov/pubmed/26937219 http://dx.doi.org/10.4196/kjpp.2016.20.2.221

Ejemplares similares

Luteolin Inhibits the Activity, Secretion and Gene Expression of MMP-3 in Cultured Articular Chondrocytes and Production of MMP-3 in the Rat Knee
por: Kang, Bun-Jung, et al.
Publicado: (2014)

Mapping Proteolytic Processing in the Secretome of Gastric Cancer-Associated Myofibroblasts Reveals Activation of MMP-1, MMP-2, and MMP-3
por: Holmberg, Christopher, et al.
Publicado: (2013)

Effect of oleanolic acid on the activity, secretion and gene expression of matrix metalloproteinase-3 in articular chondrocytes in vitro and the production of matrix metalloproteinase-3 in vivo
por: Kang, Dong-Geun, et al.
Publicado: (2017)

Betulin suppressed interleukin-1β-induced gene expression, secretion and proteolytic activity of matrix metalloproteinase in cultured articular chondrocytes and production of matrix metalloproteinase in the knee joint of rat
por: Ra, Ho Jong, et al.
Publicado: (2017)

Erratum to: Betulin suppressed interleukin-1b-induced gene expression, secretion and proteolytic activity of matrix metalloproteinase in cultured articular chondrocytes and production of matrix metalloproteinase in the knee joint of rat
por: Ra, Ho Jong, et al.
Publicado: (2017)

MT1-MMP-dependent cell migration: proteolytic and non-proteolytic mechanisms
por: Gifford, Valentina, et al.
Publicado: (2019)

Chondroprotective Effects of Wogonin in Experimental Models of Osteoarthritis in vitro and in vivo
por: Park, Jin Sung, et al.
Publicado: (2015)

Molecular Pathophysiology of Ossification of the Posterior Longitudinal Ligament (OPLL)
por: Nam, Dae Cheol, et al.
Publicado: (2019)

MMP-1, MMP-3 and MMP-10 are involved in the degradation of cartilage
por: Tolboom, TCA, et al.
Publicado: (2001)

MMP proteolytic activity regulates cancer invasiveness by modulating integrins
por: Das, Alakesh, et al.
Publicado: (2017)

Matrix Metalloproteinase-3 (MMP-3) Is an Endogenous Activator of the MMP-9 Secreted by Placental Leukocytes: Implication in Human Labor
por: Flores-Pliego, Arturo, et al.
Publicado: (2015)

Evaluation of a Triple-Helical Peptide with Quenched Fluorophores for Optical Imaging of MMP-2 and MMP-9 Proteolytic Activity
por: Zhang, Xuan, et al.
Publicado: (2014)

Leptin and Pro-Inflammatory Stimuli Synergistically Upregulate MMP-1 and MMP-3 Secretion in Human Gingival Fibroblasts
por: Williams, Rachel C., et al.
Publicado: (2016)

Expression of the metalloproteases MMP-1, MMP-2, MMP-3, MMP-9, MMP-11, TIMP-1 and TIMP-2 in angiocentric midfacial lymphomas
por: Meneses-García, Abelardo, et al.
Publicado: (2008)

Associations of matrix metalloproteinase (MMP)-8, MMP-9, and their inhibitor, tissue inhibitor of metalloproteinase-1, with obesity-related biomarkers in apparently healthy adolescent boys
por: Shin, Youn Ho, et al.
Publicado: (2014)

Dysregulation of the MMP/TIMP Proteolytic System in Subependymal Giant Cell Astrocytomas in Patients With Tuberous Sclerosis Complex: Modulation of MMP by MicroRNA-320d In Vitro
por: Bongaarts, Anika, et al.
Publicado: (2020)

Early and Late Changes of MMP-2 and MMP-9 in Bleomycin-Induced Pulmonary Fibrosis
por: Kim, Ji Young, et al.
Publicado: (2009)

Effect of Prunetin on TNF-α-Induced MUC5AC Mucin Gene Expression, Production, Degradation of IκB and Translocation of NF-κB p65 in Human Airway Epithelial Cells
por: Ryu, Jiho, et al.
Publicado: (2013)

Lupinus albus Protein Components Inhibit MMP-2 and MMP-9 Gelatinolytic Activity In Vitro and In Vivo
por: Mota, Joana, et al.
Publicado: (2021)

Salivary MMP-1, MMP-2, MMP-3 and MMP-13 Levels in Patients with Oral Lichen Planus and Squamous Cell Carcinoma
por: Nosratzehi, Tahereh, et al.
Publicado: (2017)

Association of Maternal and Fetal Single-Nucleotide Polymorphisms in Metalloproteinase (MMP1, MMP2, MMP3, and MMP9) Genes with Preeclampsia
por: Sakowicz, Agata, et al.
Publicado: (2018)

Genetic polymorphisms of MMP1, MMP3 and MMP7 gene promoter and risk of colorectal adenoma
por: Lièvre, Astrid, et al.
Publicado: (2006)

Altered Maternal Serum Matrix Metalloproteinases MMP-2, MMP-3, MMP-9, and MMP-13 in Severe Early- and Late-Onset Preeclampsia
por: Laskowska, Marzena
Publicado: (2017)

Evodiae fructus Extract Inhibits Interleukin-1β-Induced MMP-1, MMP-3, and Inflammatory Cytokine Expression by Suppressing the Activation of MAPK and STAT-3 in Human Gingival Fibroblasts In Vitro
por: Song, Hyun-Kyung, et al.
Publicado: (2021)

Correlation of MMP-3 and MMP-9 with Crohn’s Disease Activity in Children
por: Kofla-Dlubacz, Anna, et al.
Publicado: (2011)

Propeptide glycosylation and galectin‐3 binding decrease proteolytic activation of human proMMP‐9/progelatinase B
por: Boon, Lise, et al.
Publicado: (2018)

Direct anti-metastatic efficacy by the DNA enzyme Dz13 and downregulated MMP-2, MMP-9 and MT1-MMP in tumours
por: Tan, Mei Lin, et al.
Publicado: (2010)

Ginseng and Its Active Components Ginsenosides Inhibit Adipogenesis in 3T3-L1 Cells by Regulating MMP-2 and MMP-9
por: Oh, Jaeho, et al.
Publicado: (2012)

Meta-Analysis of MMP2, MMP3, and MMP9 Promoter Polymorphisms and Head and Neck Cancer Risk
por: Zhang, Caiyun, et al.
Publicado: (2013)

Correlations of MMP-1, MMP-3, and MMP-12 with the degree of atherosclerosis, plaque stability and cardiovascular and cerebrovascular events
por: Hu, Wei, et al.
Publicado: (2018)

Prunetin Relaxed Isolated Rat Aortic Rings by Blocking Calcium Channels
por: Kim, Bumjung, et al.
Publicado: (2018)

Assessment of the concentration of selected metalloproteinases (MMP-2, MMP-3, MMP-9 and MMP-13) in patients with ulcers as a complication of type 2 diabetes
por: Kupczyk, Daria, et al.
Publicado: (2020)

In Vitro Effect of Cytokines, Inducers, and Inhibitors on the Secretion of MMP-2 and MMP-9 in Hepatocarcinoma Cell Line SK-Hep-1
por: Roomi, M. Waheed, et al.
Publicado: (2019)

METTL3 promotes SMSCs chondrogenic differentiation by targeting the MMP3, MMP13, and GATA3
por: Hu, Bin, et al.
Publicado: (2023)

Associations of MMP1, MMP2 and MMP3 Genes Polymorphism with Coal Workers’ Pneumoconiosis in Chinese Han Population
por: Ji, Xiaoming, et al.
Publicado: (2015)

Inhibition of MMP1, MMP2 and MMP8 by mepacrine
por: Pollaschek, C, et al.
Publicado: (2003)

Combined Effects of MMP-7, MMP-8 and MMP-26 on the Risk of Ischemic Stroke
por: Hsieh, Fang-I, et al.
Publicado: (2019)

The polymorphisms of the MMP-1 and the MMP-3 genes and the risk of pelvic organ prolapse
por: Skorupski, Paweł, et al.
Publicado: (2012)

Proteolytic Activities of Oral Bacteria on ProMMP-9 and the Effect of Synthetic Proteinase Inhibitors
por: Jie Bao, Guang, et al.
Publicado: (2008)

Regulation of MMP-3 expression and secretion by the chemokine eotaxin-1 in human chondrocytes
por: Chao, Pin-Zhir, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_dij2j2esi8dghr5cfj0pjmcqbk