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Live imaging of osteoclast inhibition by bisphosphonates in a medaka osteoporosis model
Osteoclasts are bone-resorbing cells derived from the monocyte/macrophage lineage. Excess osteoclast activity leads to reduced bone mineral density, a hallmark of diseases such as osteoporosis. Processes that regulate osteoclast activity are therefore targeted in current osteoporosis therapies. To i...
Autores principales: | Yu, Tingsheng, Witten, Paul Eckhard, Huysseune, Ann, Buettner, Anita, To, Thuy Thanh, Winkler, Christoph |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4770141/ https://www.ncbi.nlm.nih.gov/pubmed/26704995 http://dx.doi.org/10.1242/dmm.019091 |
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