A new gestational diabetes mellitus model: hyperglycemia-induced eye malformation via inhibition of Pax6 in the chick embryo

Gestational diabetes mellitus (GDM) is one of the leading causes of fetal malformations. However, few models have been developed to study the underlying mechanisms of GDM-induced fetal eye malformation. In this study, a high concentration of glucose (0.2 mmol per egg) was injected into the air sac o...

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Detalles Bibliográficos
Autores principales: Zhang, Shi-Jie, Li, Yi-Fang, Tan, Rui-Rong, Tsoi, Bun, Huang, Wen-Shan, Huang, Yi-Hua, Tang, Xiao-Long, Hu, Dan, Yao, Nan, Yang, Xuesong, Kurihara, Hiroshi, Wang, Qi, He, Rong-Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4770145/
https://www.ncbi.nlm.nih.gov/pubmed/26744353
http://dx.doi.org/10.1242/dmm.022012

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