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Generation of brain tumours in mice by Cre-mediated recombination of neural progenitors in situ with the tamoxifen metabolite endoxifen

Targeted cell- or region-specific gene recombination is widely used in the functional analysis of genes implicated in development and disease. In the brain, targeted gene recombination has become a mainstream approach to study neurodegeneration or tumorigenesis. The use of the Cre-loxP system to stu...

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Detalles Bibliográficos
Autores principales:	Benedykcinska, Anna, Ferreira, Andreia, Lau, Joanne, Broni, Jessica, Richard-Loendt, Angela, Henriquez, Nico V., Brandner, Sebastian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Company of Biologists Ltd 2016
Materias:	Resource Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4770146/ https://www.ncbi.nlm.nih.gov/pubmed/26704996 http://dx.doi.org/10.1242/dmm.022715

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