BubbleTree: an intuitive visualization to elucidate tumoral aneuploidy and clonality using next generation sequencing data

Tumors are characterized by properties of genetic instability, heterogeneity, and significant oligoclonality. Elucidating this intratumoral heterogeneity is challenging but important. In this study, we propose a framework, BubbleTree, to characterize the tumor clonality using next generation sequenc...

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Detalles Bibliográficos
Autores principales: Zhu, Wei, Kuziora, Michael, Creasy, Todd, Lai, Zhongwu, Morehouse, Christopher, Guo, Xiang, Sebastian, Yinong, Shen, Dong, Huang, Jiaqi, Dry, Jonathan R., Xue, Feng, Jiang, Liyan, Yao, Yihong, Higgs, Brandon W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4770205/
https://www.ncbi.nlm.nih.gov/pubmed/26578606
http://dx.doi.org/10.1093/nar/gkv1102

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