Intragenic G-quadruplex structure formed in the human CD133 and its biological and translational relevance

Cancer stem cells (CSCs) have been identified in several solid malignancies and are now emerging as a plausible target for drug discovery. Beside the questionable existence of CSCs specific markers, the expression of CD133 was reported to be responsible for conferring CSC aggressiveness. Here, we id...

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Detalles Bibliográficos
Autores principales: Zizza, Pasquale, Cingolani, Chiara, Artuso, Simona, Salvati, Erica, Rizzo, Angela, D'Angelo, Carmen, Porru, Manuela, Pagano, Bruno, Amato, Jussara, Randazzo, Antonio, Novellino, Ettore, Stoppacciaro, Antonella, Gilson, Eric, Stassi, Giorgio, Leonetti, Carlo, Biroccio, Annamaria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4770210/
https://www.ncbi.nlm.nih.gov/pubmed/26511095
http://dx.doi.org/10.1093/nar/gkv1122

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