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Effects of tRNA modification on translational accuracy depend on intrinsic codon–anticodon strength
Cellular health and growth requires protein synthesis to be both efficient to ensure sufficient production, and accurate to avoid producing defective or unstable proteins. The background of misreading error frequency by individual tRNAs is as low as 2 × 10(−6) per codon but is codon-specific with so...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4770228/ https://www.ncbi.nlm.nih.gov/pubmed/26704976 http://dx.doi.org/10.1093/nar/gkv1506 |