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The conserved GTPase HflX is a ribosome splitting factor that binds to the E-site of the bacterial ribosome
Using a combination of biochemical, structural probing and rapid kinetics techniques we reveal for the first time that the universally conserved translational GTPase (trGTPase) HflX binds to the E-site of the 70S ribosome and that its GTPase activity is modulated by peptidyl transferase centre (PTC)...
Autores principales: | Coatham, Mackenzie L., Brandon, Harland E., Fischer, Jeffrey J., Schümmer, Tobias, Wieden, Hans-Joachim |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4770234/ https://www.ncbi.nlm.nih.gov/pubmed/26733579 http://dx.doi.org/10.1093/nar/gkv1524 |
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