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Multiple nucleic acid cleavage modes in divergent type III CRISPR systems

CRISPR-Cas is an RNA-guided adaptive immune system that protects bacteria and archaea from invading nucleic acids. Type III systems (Cmr, Csm) have been shown to cleave RNA targets in vitro and some are capable of transcription-dependent DNA targeting. The crenarchaeon Sulfolobus solfataricus has tw...

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Detalles Bibliográficos
Autores principales:	Zhang, Jing, Graham, Shirley, Tello, Agnes, Liu, Huanting, White, Malcolm F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2016
Materias:	Nucleic Acid Enzymes
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4770243/ https://www.ncbi.nlm.nih.gov/pubmed/26801642 http://dx.doi.org/10.1093/nar/gkw020

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