Altered DNA methylation of glycolytic and lipogenic genes in liver from obese and type 2 diabetic patients

OBJECTIVE: Epigenetic modifications contribute to the etiology of type 2 diabetes. METHOD: We performed genome-wide methylome and transcriptome analysis in liver from severely obese men with or without type 2 diabetes and non-obese men to discover aberrant pathways underlying the development of insu...

Descripción completa

Detalles Bibliográficos
Autores principales: Kirchner, Henriette, Sinha, Indranil, Gao, Hui, Ruby, Maxwell A., Schönke, Milena, Lindvall, Jessica M., Barrès, Romain, Krook, Anna, Näslund, Erik, Dahlman-Wright, Karin, Zierath, Juleen R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4770265/
https://www.ncbi.nlm.nih.gov/pubmed/26977391
http://dx.doi.org/10.1016/j.molmet.2015.12.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4770265/
https://www.ncbi.nlm.nih.gov/pubmed/26977391
http://dx.doi.org/10.1016/j.molmet.2015.12.004

Ejemplares similares