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Altered DNA methylation of glycolytic and lipogenic genes in liver from obese and type 2 diabetic patients

OBJECTIVE: Epigenetic modifications contribute to the etiology of type 2 diabetes. METHOD: We performed genome-wide methylome and transcriptome analysis in liver from severely obese men with or without type 2 diabetes and non-obese men to discover aberrant pathways underlying the development of insu...

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Detalles Bibliográficos
Autores principales:	Kirchner, Henriette, Sinha, Indranil, Gao, Hui, Ruby, Maxwell A., Schönke, Milena, Lindvall, Jessica M., Barrès, Romain, Krook, Anna, Näslund, Erik, Dahlman-Wright, Karin, Zierath, Juleen R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2016
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4770265/ https://www.ncbi.nlm.nih.gov/pubmed/26977391 http://dx.doi.org/10.1016/j.molmet.2015.12.004

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