Roles of Distal and Genic Methylation in the Development of Prostate Tumorigenesis Revealed by Genome-wide DNA Methylation Analysis

Aberrant DNA methylation at promoters is often linked to tumorigenesis. But many aspects of DNA methylation remain unexplored, including the individual roles of distal and gene body methylation, as well as their collaborative roles with promoter methylation. Here we performed a MBD-seq analysis on p...

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Detalles Bibliográficos
Autores principales: Wang, Yao, Jadhav, Rohit Ramakant, Liu, Joseph, Wilson, Desiree, Chen, Yidong, Thompson, Ian M., Troyer, Dean A., Hernandez, Javier, Shi, Huidong, Leach, Robin J., Huang, Tim H.-M., Jin, Victor X.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4770430/
https://www.ncbi.nlm.nih.gov/pubmed/26924343
http://dx.doi.org/10.1038/srep22051

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