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Parallel single-cell sequencing links transcriptional and epigenetic heterogeneity

We report scM&T-seq, a method for parallel single-cell genome-wide methylome and transcriptome sequencing, allowing discovery of associations between transcriptional and epigenetic variation. Profiling of 61 mouse embryonic stem cells confirmed known links between DNA methylation and transcripti...

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Detalles Bibliográficos
Autores principales:	Angermueller, Christof, Clark, Stephen J., Lee, Heather J., Macaulay, Iain C., Teng, Mabel J., Hu, Tim Xiaoming, Krueger, Felix, Smallwood, Sebastien, Ponting, Chris P., Voet, Thierry, Kelsey, Gavin, Stegle, Oliver, Reik, Wolf
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4770512/ https://www.ncbi.nlm.nih.gov/pubmed/26752769 http://dx.doi.org/10.1038/nmeth.3728

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