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An integrated genomics analysis of epigenetic subtypes in human breast tumors links DNA methylation patterns to chromatin states in normal mammary cells

BACKGROUND: Aberrant DNA methylation is frequently observed in breast cancer. However, the relationship between methylation patterns and the heterogeneity of breast cancer has not been comprehensively characterized. METHODS: Whole-genome DNA methylation analysis using Illumina Infinium HumanMethylat...

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Detalles Bibliográficos
Autores principales: Holm, Karolina, Staaf, Johan, Lauss, Martin, Aine, Mattias, Lindgren, David, Bendahl, Pär-Ola, Vallon-Christersson, Johan, Barkardottir, Rosa Bjork, Höglund, Mattias, Borg, Åke, Jönsson, Göran, Ringnér, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4770527/
https://www.ncbi.nlm.nih.gov/pubmed/26923702
http://dx.doi.org/10.1186/s13058-016-0685-5

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