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Recombination in pe/ppe genes contributes to genetic variation in Mycobacterium tuberculosis lineages

BACKGROUND: Approximately 10 % of the Mycobacterium tuberculosis genome is made up of two families of genes that are poorly characterized due to their high GC content and highly repetitive nature. The PE and PPE families are typified by their highly conserved N-terminal domains that incorporate prol...

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Detalles Bibliográficos
Autores principales: Phelan, Jody E., Coll, Francesc, Bergval, Indra, Anthony, Richard M., Warren, Rob, Sampson, Samantha L., Gey van Pittius, Nicolaas C., Glynn, Judith R., Crampin, Amelia C., Alves, Adriana, Bessa, Theolis Barbosa, Campino, Susana, Dheda, Keertan, Grandjean, Louis, Hasan, Rumina, Hasan, Zahra, Miranda, Anabela, Moore, David, Panaiotov, Stefan, Perdigao, Joao, Portugal, Isabel, Sheen, Patricia, de Oliveira Sousa, Erivelton, Streicher, Elizabeth M., van Helden, Paul D., Viveiros, Miguel, Hibberd, Martin L., Pain, Arnab, McNerney, Ruth, Clark, Taane G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4770551/
https://www.ncbi.nlm.nih.gov/pubmed/26923687
http://dx.doi.org/10.1186/s12864-016-2467-y

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