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Recombination in pe/ppe genes contributes to genetic variation in Mycobacterium tuberculosis lineages
BACKGROUND: Approximately 10 % of the Mycobacterium tuberculosis genome is made up of two families of genes that are poorly characterized due to their high GC content and highly repetitive nature. The PE and PPE families are typified by their highly conserved N-terminal domains that incorporate prol...
Autores principales: | Phelan, Jody E., Coll, Francesc, Bergval, Indra, Anthony, Richard M., Warren, Rob, Sampson, Samantha L., Gey van Pittius, Nicolaas C., Glynn, Judith R., Crampin, Amelia C., Alves, Adriana, Bessa, Theolis Barbosa, Campino, Susana, Dheda, Keertan, Grandjean, Louis, Hasan, Rumina, Hasan, Zahra, Miranda, Anabela, Moore, David, Panaiotov, Stefan, Perdigao, Joao, Portugal, Isabel, Sheen, Patricia, de Oliveira Sousa, Erivelton, Streicher, Elizabeth M., van Helden, Paul D., Viveiros, Miguel, Hibberd, Martin L., Pain, Arnab, McNerney, Ruth, Clark, Taane G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4770551/ https://www.ncbi.nlm.nih.gov/pubmed/26923687 http://dx.doi.org/10.1186/s12864-016-2467-y |
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