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Minimal invasive annulotomy for induction of disc degeneration and implantation of poly (lactic-co-glycolic acid) (PLGA) plugs for annular repair in a rabbit model

BACKGROUND: The rabbit disc model is useful for the study of intervertebral disc (IVD) degeneration and experimental therapeutic interventions. The annulotomy-induced disc models present several drawbacks, particularly an excessive disruption of disc integrity and a rapidly disc degeneration; theref...

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Detalles Bibliográficos
Autores principales: Xin, Long, Zhang, Chun, Zhong, Fuhua, Fan, Shunwu, Wang, Wei, Wang, Zhenbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4770696/
https://www.ncbi.nlm.nih.gov/pubmed/26924131
http://dx.doi.org/10.1186/s40001-016-0202-4