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Hes1 promotes cell proliferation and migration by activating Bmi-1 and PTEN/Akt/GSK3β pathway in human colon cancer

Hes1 is a transcription factor that influences cell proliferation and differentiation. However, the effect of Hes1 on invasiveness and the underlying mechanism remain unknown. In the current study, we found that Hes1 suppressed cell apoptosis, promoted cell growth, induced EMT phenotype and cytoskel...

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Detalles Bibliográficos
Autores principales:	Gao, Fei, Huang, Wei, Zhang, YuQin, Tang, ShaoHui, Zheng, Lin, Ma, Feng, Wang, YiMing, Tang, Hui, Li, Xin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2015
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4770728/ https://www.ncbi.nlm.nih.gov/pubmed/26452029

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