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MDP, a database linking drug response data to genomic information, identifies dasatinib and statins as a combinatorial strategy to inhibit YAP/TAZ in cancer cells
Targeted anticancer therapies represent the most effective pharmacological strategies in terms of clinical responses. In this context, genetic alteration of several oncogenes represents an optimal predictor of response to targeted therapy. Integration of large-scale molecular and pharmacological dat...
Autores principales: | Taccioli, Cristian, Sorrentino, Giovanni, Zannini, Alessandro, Caroli, Jimmy, Beneventano, Domenico, Anderlucci, Laura, Lolli, Marco, Bicciato, Silvio, Del Sal, Giannino |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4770742/ https://www.ncbi.nlm.nih.gov/pubmed/26513174 |
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