NTRK1 rearrangement in colorectal cancer patients: evidence for actionable target using patient-derived tumor cell line

BACKGROUND: We have investigated the incidence of NTRK1 rearrangements in metastatic gastrointestinal cancer patients and demonstrated the potential for clinical response of these patients to targeted therapy. METHODS: We prospectively collected tumor tissue specimens for one year and simultaneously...

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Detalles Bibliográficos
Autores principales: Lee, Su Jin, Li, Gang Gary, Kim, Seung Tae, Hong, Min Eui, Jang, Jiryeon, Yoon, Nara, Ahn, Soo Min, Murphy, Danielle, Christiansen, Jason, Wei, Ge, Hornby, Zachary, Lee, Dong Woo, Park, Joon Oh, Park, Young Suk, Lim, Ho Yeong, Hong, Sung No, Kim, Seok-Hyeong, Kang, Won Ki, Park, Keunchil, Park, Woong Yang, Kim, Kyoung-Mee, Lee, Jeeyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4770754/
https://www.ncbi.nlm.nih.gov/pubmed/26472021

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