NOX5-L can stimulate proliferation and apoptosis depending on its levels and cellular context, determining cancer cell susceptibility to cisplatin

The NADPH oxidase, NOX5, is known to stimulate cell proliferation in some cancers by generating reactive oxygen species (ROS). We show here that the long form of NOX5 (NOX5-L) also promotes cell death, and thus determines the balance of proliferation and death, in skin, breast and lung cancer cells....

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Detalles Bibliográficos
Autores principales: Dho, So Hee, Kim, Ji Young, Kwon, Eun-Soo, Lim, Jae Cheong, Park, Sung Sup, Kwon, Ki-Sun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4770769/
https://www.ncbi.nlm.nih.gov/pubmed/26513170

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