TRPC6 May Protect Renal Ischemia-Reperfusion Injury Through Inhibiting Necroptosis of Renal Tubular Epithelial Cells

BACKGROUND: The aim of this study was to explore the potential role of TRPC6 in the pathophysiology of HK-2 cell injury following ischemia reperfusion (I/R). MATERIAL/METHODS: TRPC6 expression was analyzed by immunofluorescence staining. siRNA was transfected to knockout of TRPC6 in HK-2 cells, and...

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Detalles Bibliográficos
Autores principales: Shen, BingBing, He, Yue, Zhou, Shan, Zhao, Hongwen, Mei, Mei, Wu, Xiongfei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2016
Materias:
Lab/In Vitro Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4771094/
https://www.ncbi.nlm.nih.gov/pubmed/26913924
http://dx.doi.org/10.12659/MSM.897353

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4771094/
https://www.ncbi.nlm.nih.gov/pubmed/26913924
http://dx.doi.org/10.12659/MSM.897353

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