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Overexpression of uncoupling protein 2 inhibits the high glucose-induced apoptosis of human umbilical vein endothelial cells

Ectopic apoptosis of vascular cells plays a critical role in the early stage development of diabetic retinopathy (DR). Uncoupling protein 2 (UCP2) is a mitochondrial modulator which protects against endothelial dysfunction. However, the role which UCP2 plays in endothelial apoptosis and its associat...

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Detalles Bibliográficos
Autores principales: HE, YING, LUAN, ZHOU, FU, XUNAN, XU, XUN
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4771113/
https://www.ncbi.nlm.nih.gov/pubmed/26846204
http://dx.doi.org/10.3892/ijmm.2016.2478