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Bidirectional radial Ca(2+) activity regulates neurogenesis and migration during early cortical column formation
Cortical columns are basic cellular and functional units of the cerebral cortex that are malformed in many brain disorders, but how they initially develop is not well understood. Using an optogenetic sensor in the mouse embryonic forebrain, we demonstrate that Ca(2+) fluxes propagate bidirectionally...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Association for the Advancement of Science
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4771444/ https://www.ncbi.nlm.nih.gov/pubmed/26933693 http://dx.doi.org/10.1126/sciadv.1501733 |