Distinctive Expression of Bcl-2 Factors in Regulatory T Cells Determines a Pharmacological Target to Induce Immunological Tolerance

Distinctive molecular characteristics of functionally diverse lymphocyte populations may represent novel pharmacological targets for immunotherapy. The intrinsic apoptosis pathway is differently regulated among conventional and regulatory T cells (Tregs). Targeted pharmacological modulation of this...

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Detalles Bibliográficos
Autores principales: Gabriel, Sarah Sharon, Bon, Nina, Chen, Jin, Wekerle, Thomas, Bushell, Andrew, Fehr, Thomas, Cippà, Pietro Ernesto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4771729/
https://www.ncbi.nlm.nih.gov/pubmed/26973650
http://dx.doi.org/10.3389/fimmu.2016.00073

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4771729/
https://www.ncbi.nlm.nih.gov/pubmed/26973650
http://dx.doi.org/10.3389/fimmu.2016.00073

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