Transient monosomy 7 in a chronic myelogenous leukemia patient during nilotinib therapy: a case report

Tyrosine kinase inhibitor treated chronic myelogenous leukemia patients with monosomy 7 arising in Philadelphia chromosome negative (Ph−) cells tend to evolve into MDS/AML. However, monosomy 7 in Ph− cells can be a transient finding, and it is not an absolute indication of the emergence of a new mye...

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Autores principales: Jawad, Majd D., Go, Ronald S., Ketterling, Rhett P., Begna, Kebede H., Reichard, Kaaren K., Shi, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4771850/
https://www.ncbi.nlm.nih.gov/pubmed/27014453
http://dx.doi.org/10.1002/ccr3.506
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author Jawad, Majd D.
Go, Ronald S.
Ketterling, Rhett P.
Begna, Kebede H.
Reichard, Kaaren K.
Shi, Min
author_facet Jawad, Majd D.
Go, Ronald S.
Ketterling, Rhett P.
Begna, Kebede H.
Reichard, Kaaren K.
Shi, Min
author_sort Jawad, Majd D.
collection PubMed
description Tyrosine kinase inhibitor treated chronic myelogenous leukemia patients with monosomy 7 arising in Philadelphia chromosome negative (Ph−) cells tend to evolve into MDS/AML. However, monosomy 7 in Ph− cells can be a transient finding, and it is not an absolute indication of the emergence of a new myeloid malignancy.
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spelling pubmed-47718502016-03-24 Transient monosomy 7 in a chronic myelogenous leukemia patient during nilotinib therapy: a case report Jawad, Majd D. Go, Ronald S. Ketterling, Rhett P. Begna, Kebede H. Reichard, Kaaren K. Shi, Min Clin Case Rep Case Reports Tyrosine kinase inhibitor treated chronic myelogenous leukemia patients with monosomy 7 arising in Philadelphia chromosome negative (Ph−) cells tend to evolve into MDS/AML. However, monosomy 7 in Ph− cells can be a transient finding, and it is not an absolute indication of the emergence of a new myeloid malignancy. John Wiley and Sons Inc. 2016-02-08 /pmc/articles/PMC4771850/ /pubmed/27014453 http://dx.doi.org/10.1002/ccr3.506 Text en © 2016 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial‐NoDerivs (http://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Case Reports
Jawad, Majd D.
Go, Ronald S.
Ketterling, Rhett P.
Begna, Kebede H.
Reichard, Kaaren K.
Shi, Min
Transient monosomy 7 in a chronic myelogenous leukemia patient during nilotinib therapy: a case report
title Transient monosomy 7 in a chronic myelogenous leukemia patient during nilotinib therapy: a case report
title_full Transient monosomy 7 in a chronic myelogenous leukemia patient during nilotinib therapy: a case report
title_fullStr Transient monosomy 7 in a chronic myelogenous leukemia patient during nilotinib therapy: a case report
title_full_unstemmed Transient monosomy 7 in a chronic myelogenous leukemia patient during nilotinib therapy: a case report
title_short Transient monosomy 7 in a chronic myelogenous leukemia patient during nilotinib therapy: a case report
title_sort transient monosomy 7 in a chronic myelogenous leukemia patient during nilotinib therapy: a case report
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4771850/
https://www.ncbi.nlm.nih.gov/pubmed/27014453
http://dx.doi.org/10.1002/ccr3.506
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