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Staphylococcus aureus Endocarditis with Multivalvular Involvement Secondary to an Atrial Septal Defect

Infective endocarditis is usually diagnosed using modified Duke's criteria. Our patient had a subacute presentation and a low suspicion for endocarditis during admission, unfortunately leading to her death. Despite advances in diagnostic and therapeutic measures including antibiotic therapy and...

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Autores principales: Daruwalla, Vistasp Jimmy, Sagi, Jahnavi, Tahir, Hassan, Penumetsa, Srikanth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4771888/
https://www.ncbi.nlm.nih.gov/pubmed/26989519
http://dx.doi.org/10.1155/2016/3793968
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author Daruwalla, Vistasp Jimmy
Sagi, Jahnavi
Tahir, Hassan
Penumetsa, Srikanth
author_facet Daruwalla, Vistasp Jimmy
Sagi, Jahnavi
Tahir, Hassan
Penumetsa, Srikanth
author_sort Daruwalla, Vistasp Jimmy
collection PubMed
description Infective endocarditis is usually diagnosed using modified Duke's criteria. Our patient had a subacute presentation and a low suspicion for endocarditis during admission, unfortunately leading to her death. Despite advances in diagnostic and therapeutic measures including antibiotic therapy and surgical techniques, morbidity and mortality with staphylococcal infective endocarditis remain high. Hence, we stress the significance of having a low threshold for TEE in patients with multisystem involvement due to Staphylococcus aureus that have evidence of persistent infection despite antibiotic treatment, even if the suspicion for endocarditis is low based on Duke's criteria. TEE substantially improves the sensitivity of diagnosis but may not be readily available in many medical centers. Presence of an ASD has been noted to have increased the risk of left sided endocarditis even with conditions that predispose to right sided endocarditis, particularly in patients with hemodialysis and diabetes as morbid risk factors.
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spelling pubmed-47718882016-03-17 Staphylococcus aureus Endocarditis with Multivalvular Involvement Secondary to an Atrial Septal Defect Daruwalla, Vistasp Jimmy Sagi, Jahnavi Tahir, Hassan Penumetsa, Srikanth Case Rep Cardiol Case Report Infective endocarditis is usually diagnosed using modified Duke's criteria. Our patient had a subacute presentation and a low suspicion for endocarditis during admission, unfortunately leading to her death. Despite advances in diagnostic and therapeutic measures including antibiotic therapy and surgical techniques, morbidity and mortality with staphylococcal infective endocarditis remain high. Hence, we stress the significance of having a low threshold for TEE in patients with multisystem involvement due to Staphylococcus aureus that have evidence of persistent infection despite antibiotic treatment, even if the suspicion for endocarditis is low based on Duke's criteria. TEE substantially improves the sensitivity of diagnosis but may not be readily available in many medical centers. Presence of an ASD has been noted to have increased the risk of left sided endocarditis even with conditions that predispose to right sided endocarditis, particularly in patients with hemodialysis and diabetes as morbid risk factors. Hindawi Publishing Corporation 2016 2016-02-16 /pmc/articles/PMC4771888/ /pubmed/26989519 http://dx.doi.org/10.1155/2016/3793968 Text en Copyright © 2016 Vistasp Jimmy Daruwalla et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Daruwalla, Vistasp Jimmy
Sagi, Jahnavi
Tahir, Hassan
Penumetsa, Srikanth
Staphylococcus aureus Endocarditis with Multivalvular Involvement Secondary to an Atrial Septal Defect
title Staphylococcus aureus Endocarditis with Multivalvular Involvement Secondary to an Atrial Septal Defect
title_full Staphylococcus aureus Endocarditis with Multivalvular Involvement Secondary to an Atrial Septal Defect
title_fullStr Staphylococcus aureus Endocarditis with Multivalvular Involvement Secondary to an Atrial Septal Defect
title_full_unstemmed Staphylococcus aureus Endocarditis with Multivalvular Involvement Secondary to an Atrial Septal Defect
title_short Staphylococcus aureus Endocarditis with Multivalvular Involvement Secondary to an Atrial Septal Defect
title_sort staphylococcus aureus endocarditis with multivalvular involvement secondary to an atrial septal defect
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4771888/
https://www.ncbi.nlm.nih.gov/pubmed/26989519
http://dx.doi.org/10.1155/2016/3793968
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