A Genomic Signature of Influenza Infection Shows Potential for Presymptomatic Detection, Guiding Early Therapy, and Monitoring Clinical Responses

Early, presymptomatic intervention with oseltamivir (corresponding to the onset of a published host-based genomic signature of influenza infection) resulted in decreased overall influenza symptoms (aggregate symptom scores of 23.5 vs 46.3), more rapid resolution of clinical disease (20 hours earlier...

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Detalles Bibliográficos
Autores principales: McClain, Micah T., Nicholson, Bradly P., Park, Lawrence P., Liu, Tzu-Yu, Hero, Alfred O., Tsalik, Ephraim L., Zaas, Aimee K., Veldman, Timothy, Hudson, Lori L., Lambkin-Williams, Robert, Gilbert, Anthony, Burke, Thomas, Nichols, Marshall, Ginsburg, Geoffrey S., Woods, Christopher W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Brief Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4771939/
https://www.ncbi.nlm.nih.gov/pubmed/26933666
http://dx.doi.org/10.1093/ofid/ofw007

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