Yessotoxin, a Promising Therapeutic Tool

Yessotoxin (YTX) is a polyether compound produced by dinoflagellates and accumulated in filter feeding shellfish. No records about human intoxications induced by this compound have been published, however it is considered a toxin. Modifications in second messenger levels, protein levels, immune cell...

Descripción completa

Detalles Bibliográficos
Autores principales: Alfonso, Amparo, Vieytes, Mercedes R., Botana, Luis M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4771983/
https://www.ncbi.nlm.nih.gov/pubmed/26828502
http://dx.doi.org/10.3390/md14020030
Descripción
Sumario:Yessotoxin (YTX) is a polyether compound produced by dinoflagellates and accumulated in filter feeding shellfish. No records about human intoxications induced by this compound have been published, however it is considered a toxin. Modifications in second messenger levels, protein levels, immune cells, cytoskeleton or activation of different cellular death types have been published as consequence of YTX exposure. This review summarizes the main intracellular pathways modulated by YTX and their pharmacological and therapeutic implications.

Ejemplares similares