Yessotoxin, a Promising Therapeutic Tool

Yessotoxin (YTX) is a polyether compound produced by dinoflagellates and accumulated in filter feeding shellfish. No records about human intoxications induced by this compound have been published, however it is considered a toxin. Modifications in second messenger levels, protein levels, immune cell...

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Detalles Bibliográficos
Autores principales: Alfonso, Amparo, Vieytes, Mercedes R., Botana, Luis M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4771983/
https://www.ncbi.nlm.nih.gov/pubmed/26828502
http://dx.doi.org/10.3390/md14020030
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author Alfonso, Amparo
Vieytes, Mercedes R.
Botana, Luis M.
author_facet Alfonso, Amparo
Vieytes, Mercedes R.
Botana, Luis M.
author_sort Alfonso, Amparo
collection PubMed
description Yessotoxin (YTX) is a polyether compound produced by dinoflagellates and accumulated in filter feeding shellfish. No records about human intoxications induced by this compound have been published, however it is considered a toxin. Modifications in second messenger levels, protein levels, immune cells, cytoskeleton or activation of different cellular death types have been published as consequence of YTX exposure. This review summarizes the main intracellular pathways modulated by YTX and their pharmacological and therapeutic implications.
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spelling pubmed-47719832016-03-08 Yessotoxin, a Promising Therapeutic Tool Alfonso, Amparo Vieytes, Mercedes R. Botana, Luis M. Mar Drugs Review Yessotoxin (YTX) is a polyether compound produced by dinoflagellates and accumulated in filter feeding shellfish. No records about human intoxications induced by this compound have been published, however it is considered a toxin. Modifications in second messenger levels, protein levels, immune cells, cytoskeleton or activation of different cellular death types have been published as consequence of YTX exposure. This review summarizes the main intracellular pathways modulated by YTX and their pharmacological and therapeutic implications. MDPI 2016-01-28 /pmc/articles/PMC4771983/ /pubmed/26828502 http://dx.doi.org/10.3390/md14020030 Text en © 2016 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons by Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Alfonso, Amparo
Vieytes, Mercedes R.
Botana, Luis M.
Yessotoxin, a Promising Therapeutic Tool
title Yessotoxin, a Promising Therapeutic Tool
title_full Yessotoxin, a Promising Therapeutic Tool
title_fullStr Yessotoxin, a Promising Therapeutic Tool
title_full_unstemmed Yessotoxin, a Promising Therapeutic Tool
title_short Yessotoxin, a Promising Therapeutic Tool
title_sort yessotoxin, a promising therapeutic tool
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4771983/
https://www.ncbi.nlm.nih.gov/pubmed/26828502
http://dx.doi.org/10.3390/md14020030
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