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Molecular characterization of HIV-1 Nef and ACOT8 interaction: insights from in silico structural predictions and in vitro functional assays

HIV-1 Nef interacts with several cellular proteins, among which the human peroxisomal thioesterase 8 (ACOT8). This interaction may be involved in the endocytosis regulation of membrane proteins and might modulate lipid composition in membrane rafts. Nef regions involved in the interaction have been...

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Detalles Bibliográficos
Autores principales:	Serena, Michela, Giorgetti, Alejandro, Busato, Mirko, Gasparini, Francesca, Diani, Erica, Romanelli, Maria Grazia, Zipeto, Donato
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4772117/ https://www.ncbi.nlm.nih.gov/pubmed/26927806 http://dx.doi.org/10.1038/srep22319

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