Attenuated Leishmania induce pro-inflammatory mediators and influence leishmanicidal activity by p38 MAPK dependent phagosome maturation in Leishmania donovani co-infected macrophages

Promastigote form of Leishmania, an intracellular pathogen, delays phagosome maturation and resides inside macrophages. But till date limited study has been done to manipulate the phagosomal machinery of macrophages to restrict Leishmania growth. Attenuated Leishmania strain exposed RAW 264.7 cells...

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Detalles Bibliográficos
Autores principales: Banerjee, Somenath, Bose, Dipayan, Chatterjee, Nabanita, Das, Subhadip, Chakraborty, Sreeparna, Das, Tanya, Saha, Krishna Das
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4772118/
https://www.ncbi.nlm.nih.gov/pubmed/26928472
http://dx.doi.org/10.1038/srep22335

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