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Gene dysregulation is restored in the Parkinson’s disease MPTP neurotoxic mice model upon treatment of the therapeutic drug Cu(II)(atsm)

The administration of MPTP selectively targets the dopaminergic system resulting in Parkinsonism-like symptoms and is commonly used as a mice model of Parkinson’s disease. We previously demonstrated that the neuroprotective compound Cu(II)(atsm) rescues nigral cell loss and improves dopamine metabol...

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Detalles Bibliográficos
Autores principales:	Cheng, Lesley, Quek, Camelia Y. J., Hung, Lin W., Sharples, Robyn A., Sherratt, Nicki A., Barnham, Kevin J., Hill, Andrew F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4772163/ https://www.ncbi.nlm.nih.gov/pubmed/26928495 http://dx.doi.org/10.1038/srep22398

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