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Analysis of secondary structural elements in human microRNA hairpin precursors

BACKGROUND: MicroRNAs (miRNAs) regulate gene expression by targeting complementary mRNAs for destruction or translational repression. Aberrant expression of miRNAs has been associated with various diseases including cancer, thus making them interesting therapeutic targets. The composite of secondary...

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Detalles Bibliográficos
Autores principales: Liu, Biao, Childs-Disney, Jessica L., Znosko, Brent M., Wang, Dan, Fallahi, Mohammad, Gallo, Steven M., Disney, Matthew D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4772329/
https://www.ncbi.nlm.nih.gov/pubmed/26928172
http://dx.doi.org/10.1186/s12859-016-0960-6