Exploiting HIV-1 protease and reverse transcriptase cross-resistance information for improved drug resistance prediction by means of multi-label classification

BACKGROUND: Antiretroviral therapy is essential for human immunodeficiency virus (HIV) infected patients to inhibit viral replication and therewith to slow progression of disease and prolong a patient’s life. However, the high mutation rate of HIV can lead to a fast adaptation of the virus under dru...

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Detalles Bibliográficos
Autores principales: Riemenschneider, Mona, Senge, Robin, Neumann, Ursula, Hüllermeier, Eyke, Heider, Dominik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4772363/
https://www.ncbi.nlm.nih.gov/pubmed/26933450
http://dx.doi.org/10.1186/s13040-016-0089-1

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