Inhibition of miR-154 Protects Against Cardiac Dysfunction and Fibrosis in a Mouse Model of Pressure Overload

Expression of miR-154 is upregulated in the diseased heart and was previously shown to be upregulated in the lungs of patients with pulmonary fibrosis. However, the role of miR-154 in a model of sustained pressure overload-induced cardiac hypertrophy and fibrosis had not been assessed. To examine th...

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Detalles Bibliográficos
Autores principales: Bernardo, Bianca C., Nguyen, Sally S., Gao, Xiao-Ming, Tham, Yow Keat, Ooi, Jenny Y. Y., Patterson, Natalie L., Kiriazis, Helen, Su, Yidan, Thomas, Colleen J., Lin, Ruby C. Y., Du, Xiao-Jun, McMullen, Julie R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4772383/
https://www.ncbi.nlm.nih.gov/pubmed/26928825
http://dx.doi.org/10.1038/srep22442

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