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A triterpenoid from wild bitter gourd inhibits breast cancer cells

The antitumor activity of 3β,7β,25-trihydroxycucurbita-5,23(E)-dien-19-al (TCD), a triterpenoid isolated from wild bitter gourd, in breast cancer cells was investigated. TCD suppressed the proliferation of MCF-7 and MDA-MB-231 breast cancer cells with IC(50) values at 72 h of 19 and 23 μM, respectiv...

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Detalles Bibliográficos
Autores principales: Bai, Li-Yuan, Chiu, Chang-Fang, Chu, Po-Chen, Lin, Wei-Yu, Chiu, Shih-Jiuan, Weng, Jing-Ru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4772478/
https://www.ncbi.nlm.nih.gov/pubmed/26926586
http://dx.doi.org/10.1038/srep22419