Uni-axial stretch induces actin stress fiber reorganization and activates c-Jun NH(2) terminal kinase via RhoA and Rho kinase in human bladder smooth muscle cells

BACKGROUND: Excessive mechanical overload may be involved in bladder wall remodelling. Since the activity of Rho kinase is known to be upregulated in the obstructed bladder, we investigate the roles of the RhoA/Rho kinase pathway in mechanical overloaded bladder smooth muscle cells. METHODS: Human b...

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Detalles Bibliográficos
Autores principales: Kushida, Nobuhiro, Yamaguchi, Osamu, Kawashima, Yohei, Akaihata, Hidenori, Hata, Junya, Ishibashi, Kei, Aikawa, Ken, Kojima, Yoshiyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4772493/
https://www.ncbi.nlm.nih.gov/pubmed/26928204
http://dx.doi.org/10.1186/s12894-016-0127-9

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