Mutations that prevent or mimic persistent post-translational modifications of the histone H3 globular domain cause lethality and growth defects in Drosophila

BACKGROUND: Understanding the function of histone post-translational modifications is the key to deciphering how genomic activities are regulated. Among the least well-understood histone modifications in vivo are those that occur on the surface of the globular domain of histones, despite their causi...

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Detalles Bibliográficos
Autores principales: Graves, Hillary K., Wang, Pingping, Lagarde, Matthew, Chen, Zhihong, Tyler, Jessica K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4772521/
https://www.ncbi.nlm.nih.gov/pubmed/26933451
http://dx.doi.org/10.1186/s13072-016-0059-3

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