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Immune responses to Mycobacterial heat shock protein 70 accompany self-reactivity to human BiP in rheumatoid arthritis

Rheumatoid arthritis (RA) is an autoimmune disease, and a member of human heat shock protein (HSP) 70 protein family, Binding Immunoglobulin Protein (BiP), has been identified as an important autoantigen for T and B cells. We herein focused on Mycobacterial (Myc) HSPs and immune responses to MycHSPs...

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Detalles Bibliográficos
Autores principales: Shoda, Hirofumi, Hanata, Norio, Sumitomo, Shuji, Okamura, Tomohisa, Fujio, Keishi, Yamamoto, Kazuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4772543/
https://www.ncbi.nlm.nih.gov/pubmed/26927756
http://dx.doi.org/10.1038/srep22486